BDBM809140 6-amino-N-[(1S,2S)-2-({4-[(1S)-1-{4-[(2S)-2,3-dihydroxypropyl]piperazin-1-yl}-3,3-dimethyl-2,3-dihydro-1H-inden-5-yl]phenyl}methoxy)cyclopentyl]-2'-fluoro[3,3'-bipyridine]-5-carboxamide::US20260146035, Example 168

SMILES CC1(C)C[C@H](N2CCN(C[C@H](O)CO)CC2)c2ccc(-c3ccc(CO[C@H]4CCC[C@@H]4NC(=O)c4cc(-c5cccnc5F)cnc4N)cc3)cc21

InChI Key InChIKey=FUIFURJIUQPHGJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 809140   

TargetTyrosine-protein kinase Mer(Human)
Dong-A St Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 809140BDBM809140(6-amino-N-[(1S,2S)-2-({4-[(1S)-1-{4-[(2S)-2,3-dihy...)
Affinity DataIC50: 10nMAssay Description:The reason was carried out in white low volume 384-well plate (Corning, USA) with 25 nL compounds in dimethyl sulfoxide in each well. To measure the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase receptor UFO(Human)
Dong-A St Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 809140BDBM809140(6-amino-N-[(1S,2S)-2-({4-[(1S)-1-{4-[(2S)-2,3-dihy...)
Affinity DataIC50: 10nMAssay Description:The reason was carried out in white low volume 384-well plate (Corning, USA) with 25 nL compounds in dimethyl sulfoxide in each well. To measure the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2026
Entry Details
US Patent

TargetTyrosinase(Human)
Dong-A St Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 809140BDBM809140(6-amino-N-[(1S,2S)-2-({4-[(1S)-1-{4-[(2S)-2,3-dihy...)
Affinity DataIC50: 55nMAssay Description:The reason was carried out in white low volume 384-well plate (Corning, USA) with 25 nL compounds in dimethyl sulfoxide in each well. To measure the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2026
Entry Details
US Patent