BDBM809216 (S)-4-(1-(3-(difluoromethyl)-5-(3-ethylphenoxy)-1-methyl-1H-pyrazole-4-carboxamido)ethyl)benzoic Acid::US12643889, Compound I-1

SMILES CCc1cccc(Oc2c(C(=O)N[C@@H](C)c3ccc(C(=O)O)cc3)c(C(F)F)nn2C)c1

InChI Key InChIKey=JTTQWARZACYLAZ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 809216   

TargetProstaglandin E2 receptor EP4 subtype(Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandChemical structure of BindingDB Monomer ID 809216BDBM809216((S)-4-(1-(3-(difluoromethyl)-5-(3-ethylphenoxy)-1-...)
Affinity DataKi:  8.90nMAssay Description:The bindings, to the radioligand EP4, of a control compound and the compounds prepared by Examples 1 to 43 were tested using recombinant human EP4 re...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/19/2026
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandChemical structure of BindingDB Monomer ID 809216BDBM809216((S)-4-(1-(3-(difluoromethyl)-5-(3-ethylphenoxy)-1-...)
Affinity DataIC50: 16nMAssay Description:The bindings, to the radioligand EP4, of a control compound and the compounds prepared by Examples 1 to 43 were tested using recombinant human EP4 re...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/19/2026
Entry Details
US Patent