BDBM809235 (4Z)-4-[(1,3-benzothiazol-6-yl)methylidene]-2-[(4-methoxyphenyl)amino]-4,5-dihydro-1H-imidazol-5-one::(Z)-5-(benzo[d]thiazol-6-ylmethylene)-2-((4-methoxyphenyl)amino)-3,5-dihydro-4H-imidazol-4-one::US12643887, Example 25
SMILES COc1ccc(NC2=N/C(=C\c3ccc4ncsc4c3)C(=O)N2)cc1
InChI Key InChIKey=RGDMFKYOBRJLPZ-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 809235
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Tongji University
US Patent
Tongji University
US Patent
Affinity DataIC50: 100nMAssay Description:Briefly, DYRK1A (3 nM) in the enzymatic buffer solutions (40 mM Tris, pH 7.5, 20 mM MgCl2, 0.1 mg/ml BSA, 50 μM DTT) were mixed with various concentr...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 100nMAssay Description:Briefly, CLK1 (16 nM) in the enzymatic buffer solutions (40 mM Tris, pH 7.5, 20 mM MgCl2, 0.1 mg/ml BSA, 50 μM DTT) were mixed with various concentra...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 550nMAssay Description:Briefly, HIPK1 (4 nM) in the enzymatic buffer solutions (40 mM Tris, pH 7.5, 20 mM MgCl2, 0.1 mg/ml BSA, 50 μM DTT) were mixed with various concentra...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 550nMAssay Description:Briefly, HIPK2 (1 nM) in the enzymatic buffer solutions (40 mM Tris, pH 7.5, 20 mM MgCl2, 0.1 mg/ml BSA, 50 μM DTT) were mixed with various concentra...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 1.00E+4nMAssay Description:Briefly, GSK3 beta (4 nM) in the enzymatic buffer solutions (40 mM Tris, pH 7.5, 20 mM MgCl2, 0.1 mg/ml BSA, 50 μM DTT) were mixed with various conce...More data for this Ligand-Target Pair
Ligand Info