BDBM809293 (4Z)-2-[(1,3-benzothiazol-6-yl)(2-methoxyethyl)amino]-4-[(1,3-benzothiazol-6-yl)methylidene]-4,5-dihydro-1H-imidazol-5-one::(Z)-2-(benzo[d]thiazol-6-yl(2-methoxyethyl)amino)-5-(benzo[d]thiazol-6-ylmethylene)-3,5-dihydro-4H-imidazol-4-one::US12643887, Example 89

SMILES COCCN(C1=N/C(=C\c2ccc3ncsc3c2)C(=O)N1)c1ccc2ncsc2c1

InChI Key InChIKey=XORUAKAUDHXJSE-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 809293   

TargetDual specificity protein kinase CLK1 [129-484](Human)
Tongji University

US Patent
LigandChemical structure of BindingDB Monomer ID 809293BDBM809293((Z)-2-(benzo[d]thiazol-6-yl(2-methoxyethyl)amino)-...)
Affinity DataIC50: 100nMAssay Description:Briefly, CLK1 (16 nM) in the enzymatic buffer solutions (40 mM Tris, pH 7.5, 20 mM MgCl2, 0.1 mg/ml BSA, 50 μM DTT) were mixed with various concentra...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/19/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 809293BDBM809293((Z)-2-(benzo[d]thiazol-6-yl(2-methoxyethyl)amino)-...)
Affinity DataIC50: 550nMAssay Description:Briefly, DYRK1A (3 nM) in the enzymatic buffer solutions (40 mM Tris, pH 7.5, 20 mM MgCl2, 0.1 mg/ml BSA, 50 μM DTT) were mixed with various concentr...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/19/2026
Entry Details
US Patent

TargetHomeodomain-interacting protein kinase 2 [1-640](Human)
Tongji University

US Patent
LigandChemical structure of BindingDB Monomer ID 809293BDBM809293((Z)-2-(benzo[d]thiazol-6-yl(2-methoxyethyl)amino)-...)
Affinity DataIC50: 550nMAssay Description:Briefly, HIPK2 (1 nM) in the enzymatic buffer solutions (40 mM Tris, pH 7.5, 20 mM MgCl2, 0.1 mg/ml BSA, 50 μM DTT) were mixed with various concentra...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/19/2026
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Tongji University

US Patent
LigandChemical structure of BindingDB Monomer ID 809293BDBM809293((Z)-2-(benzo[d]thiazol-6-yl(2-methoxyethyl)amino)-...)
Affinity DataIC50: 5.50E+3nMAssay Description:Briefly, GSK3 beta (4 nM) in the enzymatic buffer solutions (40 mM Tris, pH 7.5, 20 mM MgCl2, 0.1 mg/ml BSA, 50 μM DTT) were mixed with various conce...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/19/2026
Entry Details
US Patent

TargetHomeodomain-interacting protein kinase 1 [156-555](Human)
Tongji University

US Patent
LigandChemical structure of BindingDB Monomer ID 809293BDBM809293((Z)-2-(benzo[d]thiazol-6-yl(2-methoxyethyl)amino)-...)
Affinity DataIC50: 5.50E+3nMAssay Description:Briefly, HIPK1 (4 nM) in the enzymatic buffer solutions (40 mM Tris, pH 7.5, 20 mM MgCl2, 0.1 mg/ml BSA, 50 μM DTT) were mixed with various concentra...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/19/2026
Entry Details
US Patent