BDBM809313 (S)-4-(1-(3-(difluoromethyl)-1-methyl-5-(3-(2,2,2-trifluoroethyl)phenoxy)-1H-pyrazole-4-carboxamido)ethyl)benzoic Acid::US12643889, Compound I-6

SMILES C[C@H](NC(=O)c1c(C(F)F)nn(C)c1Oc1cccc(CC(F)(F)F)c1)c1ccc(C(=O)O)cc1

InChI Key InChIKey=ZEVSPHAKPSTUHJ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 809313   

TargetProstaglandin E2 receptor EP4 subtype(Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandChemical structure of BindingDB Monomer ID 809313BDBM809313((S)-4-(1-(3-(difluoromethyl)-1-methyl-5-(3-(2,2,2-...)
Affinity DataKi:  5.80nMAssay Description:The bindings, to the radioligand EP4, of a control compound and the compounds prepared by Examples 1 to 43 were tested using recombinant human EP4 re...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/19/2026
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandChemical structure of BindingDB Monomer ID 809313BDBM809313((S)-4-(1-(3-(difluoromethyl)-1-methyl-5-(3-(2,2,2-...)
Affinity DataIC50: 11nMAssay Description:The bindings, to the radioligand EP4, of a control compound and the compounds prepared by Examples 1 to 43 were tested using recombinant human EP4 re...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/19/2026
Entry Details
US Patent