BDBM809340 (S)-6-chloro-2-((5-methyl- [2,5$#8243;-bipyrimidin]-2$#8243;- yl)amino)2,3-dihydro-1H- indene-4-carbonitrile'::US12643890, Example 20

SMILES Cc1cnc(-c2cnc(N[C@H]3Cc4cc(Cl)cc(C#N)c4C3)nc2)nc1

InChI Key InChIKey=VOGLESTZJITONZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 809340   

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 809340BDBM809340((S)-6-chloro-2-((5-methyl- [2,5$#8243;-bipyrimidin...)
Affinity DataIC50: 14nMAssay Description:ATX is diluted to 2.2 nM in assay buffer. Choline oxidase and horseradish peroxidase are diluted to 7.3 U/ml and 14.7 U/ml, respectively. 18:1 LPC an...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/19/2026
Entry Details
US Patent