BDBM809341 (S)-6-chloro-2-[[5-(3-methyl- 1,2,4-triazol-1-yl)pyrimidin-2- yl]amino]-2,3-dihydro-1H- indene-4-carbonitrile::US12643890, Example 21

SMILES Cc1ncn(-c2cnc(N[C@H]3Cc4cc(Cl)cc(C#N)c4C3)nc2)n1

InChI Key InChIKey=AWORMEMGOLWYOZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 809341   

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 809341BDBM809341((S)-6-chloro-2-[[5-(3-methyl- 1,2,4-triazol-1-yl)p...)
Affinity DataIC50: 12nMAssay Description:ATX is diluted to 2.2 nM in assay buffer. Choline oxidase and horseradish peroxidase are diluted to 7.3 U/ml and 14.7 U/ml, respectively. 18:1 LPC an...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/19/2026
Entry Details
US Patent