BDBM809383 4-(((2-(Benzylamino)-5-phenylthieno[2,3-d]pyrimidin-4-yl)amino)methyl)benzenesulfonamide::US12643910, Compound 1.41

SMILES NS(=O)(=O)c1ccc(CNc2nc(NCc3ccccc3)nc3scc(-c4ccccc4)c23)cc1

InChI Key InChIKey=HCNAHXMBPKOCCS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 809383   

TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 809383BDBM809383(4-(((2-(Benzylamino)-5-phenylthieno[2,3-d]pyrimidi...)
Affinity DataIC50: 100nMAssay Description:Ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) hydrolyzes ATP, breaking it down into 5′-AMP and pyrophosphate. The 5′-AMP formed from the...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/19/2026
Entry Details
US Patent