BDBM809392 4-((2-(3-Hydroxypropyl)amino-5-phenylthieno[2,3-d]pyrimidin-4-yl)aminomethyl)benzenesulfonamide::US12643910, Compound 1.51

SMILES NS(=O)(=O)c1ccc(CNc2nc(NCCCO)nc3scc(-c4ccccc4)c23)cc1

InChI Key InChIKey=LFUAYWZYZGJHDK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 809392   

TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 809392BDBM809392(4-((2-(3-Hydroxypropyl)amino-5-phenylthieno[2,3-d]...)
Affinity DataIC50: 100nMAssay Description:Ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) hydrolyzes ATP, breaking it down into 5′-AMP and pyrophosphate. The 5′-AMP formed from the...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/19/2026
Entry Details
US Patent