BDBM809588 (E)-1-(7-Bromothieno[3,2-d]pyrimidin-4-yl)-N-(3-(4-methylpyridin-3-yl)allyl)piperidin-4-amine::US12643910, Compound 3.62

SMILES Cc1ccncc1/C=C/CNC1CCN(c2ncnc3c(Br)csc23)CC1

InChI Key InChIKey=GEJKWJSBQKYNQO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 809588   

TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 809588BDBM809588((E)-1-(7-Bromothieno[3,2-d]pyrimidin-4-yl)-N-(3-(4...)
Affinity DataIC50: 100nMAssay Description:Ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) hydrolyzes ATP, breaking it down into 5′-AMP and pyrophosphate. The 5′-AMP formed from the...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/19/2026
Entry Details
US Patent