BDBM809613 US12643912, Example 9a

SMILES Cc1c2ccc3c1nnn3CCCCOc1ccc3c(c1)CN(Cc1cc(ccc1Cl)[C@@H]2CC(=O)O)S(=O)(=O)O3

InChI Key InChIKey=PYHSGQQAMYPRMC-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 809613   

TargetKelch-like ECH-associated protein 1 [321-624](Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 809613BDBM809613(US12643912, Example 9a)
Affinity DataKd:  2.12nMAssay Description:Binding assay to Kelch domain of KEAP1 was performed by Surface Plasmon Resonance (SPR) on a Biacore T200 (GE Healthcare) at 25° C. using CM5 chip. H...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/19/2026
Entry Details
US Patent