BDBM809634 US12643912, Example 20a

SMILES Cc1ccc2cc1[C@@H](C)N1Cc3cc(ccc3OS1(=O)=O)OCCCCCn1nnc3c(C)c(ccc31)[C@H]2CC(=O)O

InChI Key InChIKey=ZRFANOASNVBMSM-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 809634   

TargetKelch-like ECH-associated protein 1 [321-624](Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 809634BDBM809634(US12643912, Example 20a)
Affinity DataKd:  0.549nMAssay Description:Binding assay to Kelch domain of KEAP1 was performed by Surface Plasmon Resonance (SPR) on a Biacore T200 (GE Healthcare) at 25° C. using CM5 chip. H...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/19/2026
Entry Details
US Patent