BDBM809643 US12643912, Example 24b

SMILES COCCC1CCOc2ccc3c(c2)CN([C@H](C)c2cc(ccc2C)[C@H](CC(=O)O)c2ccc4c(nnn4C1)c2C)S(=O)(=O)O3

InChI Key InChIKey=SPEUGYDKOZDZPO-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 809643   

TargetKelch-like ECH-associated protein 1 [321-624](Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 809643BDBM809643(US12643912, Example 24b)
Affinity DataKd:  1.23nMAssay Description:Binding assay to Kelch domain of KEAP1 was performed by Surface Plasmon Resonance (SPR) on a Biacore T200 (GE Healthcare) at 25° C. using CM5 chip. H...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/19/2026
Entry Details
US Patent