BDBM809684 US12643912, Example 55b

SMILES [2H]C([2H])(C(=O)O)[C@H]1c2ccc(C)c(c2)CN2Cc3cc(ccc3OS2(=O)=O)OCCCCn2nnc3c(C)c1ccc32

InChI Key InChIKey=MBYGSCJIFUUTNN-DOBBINOXSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 809684   

TargetKelch-like ECH-associated protein 1 [321-624](Human)
Les Laboratoires Servier

US Patent
LigandChemical structure of BindingDB Monomer ID 809684BDBM809684(US12643912, Example 55b)
Affinity DataKd:  2.5nMAssay Description:Binding assay to Kelch domain of KEAP1 was performed by Surface Plasmon Resonance (SPR) on a Biacore T200 (GE Healthcare) at 25° C. using CM5 chip. H...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/19/2026
Entry Details
US Patent