BDBM81441 CDK Inhibitor, 14
SMILES Cc1c(sc(=O)n1C)-c1ccnc(Nc2ccc(cc2)N2CCNCC2)n1
InChI Key InChIKey=CGGMDMYBCWDOLZ-UHFFFAOYSA-N
Data 8 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 81441
Affinity DataKi: 0.380nMAssay Description:Kinase assay using cyclin-dependant kinases (CDK).More data for this Ligand-Target Pair
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
University of Nebraska Medical Center
Curated by ChEMBL
University of Nebraska Medical Center
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Inhibition of recombinant human His-tagged CDK9/cyclin T1 expressed in baculovirus infected sf9 cells using (biotinyl-Ahx-(Tyr-Ser-ProThr-Ser-Pro-Ser...More data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Kinase assay using cyclin-dependant kinases (CDK).More data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Inhibition of CDK7 (unknown origin) using (biotinyl-Ahx-(Tyr-Ser-ProThr-Ser-Pro-Ser)4-NH2 as substrate after 45 mins by [gamma-32P]ATP based microbet...More data for this Ligand-Target Pair
Affinity DataKi: 68nMAssay Description:Kinase assay using cyclin-dependant kinases (CDK).More data for this Ligand-Target Pair
Affinity DataKi: 149nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 149nMAssay Description:Kinase assay using cyclin-dependant kinases (CDK).More data for this Ligand-Target Pair
Affinity DataKi: 449nMAssay Description:Kinase assay using cyclin-dependant kinases (CDK).More data for this Ligand-Target Pair