BDBM8167 4-{2-phenylpyrazolo[1,5-a]pyridazin-3-yl}-N-[3-(trifluoromethyl)phenyl]pyrimidin-2-amine::pyrazolo[1,5-b]pyridazine deriv. 58

SMILES FC(F)(F)c1cccc(Nc2nccc(n2)-c2c(nn3ncccc23)-c2ccccc2)c1

InChI Key InChIKey=BLAJHXAFHKBZSN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 8167   

TargetGlycogen synthase kinase-3 beta(Human)
Glaxosmithkline

LigandPNGBDBM8167(4-{2-phenylpyrazolo[1,5-a]pyridazin-3-yl}-N-[3-(tr...)
Affinity DataIC50: 12nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-32P] ATP. Af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Glaxosmithkline

LigandPNGBDBM8167(4-{2-phenylpyrazolo[1,5-a]pyridazin-3-yl}-N-[3-(tr...)
Affinity DataIC50: 2.00E+4nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-32P] ATP. Af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2006
Entry Details Article
PubMed