BDBM82113 1,3,5-Triazaspiro[5.5]undeca-1,3-diene-2,4-diamine, IIb

SMILES NC1=NC2(CCCCC2)N(OCc2ccccc2)C(N)=N1

InChI Key InChIKey=MISVUIHZGPYQIP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 82113   

TargetDihydrofolate reductase(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM82113(1,3,5-Triazaspiro[5.5]undeca-1,3-diene-2,4-diamine...)
Affinity DataIC50: 1.79E+3nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
National University of Singapore

LigandPNGBDBM82113(1,3,5-Triazaspiro[5.5]undeca-1,3-diene-2,4-diamine...)
Affinity DataIC50: 1.79E+3nMAssay Description:Inhibition activity using bovine dihydrofolate reductase (DHFR).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed