BDBM83296 2-[[4-(3-chlorophenyl)-1-piperazinyl]methyl]-1-methylbenzimidazole::2-[[4-(3-chlorophenyl)piperazin-1-yl]methyl]-1-methyl-benzimidazole::2-[[4-(3-chlorophenyl)piperazin-1-yl]methyl]-1-methylbenzimidazole::2-[[4-(3-chlorophenyl)piperazino]methyl]-1-methyl-benzimidazole::2-{[4-(3-chlorophenyl)-1-piperazinyl]methyl}-1-methyl-1H-benzimidazole::MLS000547944::SMR000115764::cid_851992

SMILES Cc1ncc(O)c(C)c1-n1c(N)c(C(N)=O)c2cc(Cl)cnc21

InChI Key InChIKey=DGGCMRLNBJCGGO-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 83296   

TargetMembrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 83296BDBM83296(US20250388583, Compound 543)
Affinity DataIC50: 50nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent

TargetTyrosine-protein kinase Lck(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 83296BDBM83296(US20250388583, Compound 543)
Affinity DataIC50: 550nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent