BDBM83311 7-chloranyl-3-(pyridin-3-ylmethyl)-2-sulfanylidene-1H-quinazolin-4-one::7-chloro-3-(3-pyridinylmethyl)-2-sulfanylidene-1H-quinazolin-4-one::7-chloro-3-(3-pyridylmethyl)-2-thioxo-1H-quinazolin-4-one::7-chloro-3-(pyridin-3-ylmethyl)-2-sulfanylidene-1H-quinazolin-4-one::MLS000520856::SMR000131265::cid_4305845

SMILES Cc1cc2c(C(N)=O)c(N)n(-c3c(C)ncc(O)c3C)c2nc1C

InChI Key InChIKey=FMLUPHGXWLZZFA-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 83311   

TargetMembrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 83311BDBM83311(US20250388583, Compound 566 | US20260001879, Compo...)
Affinity DataIC50: 50nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent

TargetMyelin transcription factor 1(Human)
Broad Institute

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 83311BDBM83311(US20250388583, Compound 566 | US20260001879, Compo...)
Affinity DataIC50: 200nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2026
Entry Details
US Patent

TargetTyrosine-protein kinase Lck(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 83311BDBM83311(US20250388583, Compound 566 | US20260001879, Compo...)
Affinity DataIC50: 550nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent