BDBM83315 2-[5-(4-ethylpiperazin-1-yl)-2-nitro-phenyl]sulfanyl-1H-benzimidazole::2-[5-(4-ethylpiperazin-1-yl)-2-nitrophenyl]sulfanyl-1H-benzimidazole::2-[[5-(4-ethyl-1-piperazinyl)-2-nitrophenyl]thio]-1H-benzimidazole::2-[[5-(4-ethylpiperazino)-2-nitro-phenyl]thio]-1H-benzimidazole::2-{[5-(4-ethyl-1-piperazinyl)-2-nitrophenyl]thio}-1H-benzimidazole::MLS000579941::SMR000199181::cid_2947809

SMILES Cc1ccc(O)c(C)c1-n1c(N)c(C(N)=O)c2cncnc21

InChI Key InChIKey=IUEQXWALPVLROR-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 83315   

TargetMembrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 83315BDBM83315(US20250388583, Compound 572)
Affinity DataIC50: 50nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent