BDBM83321 7-(2-methylphenyl)-5-(4-methylphenyl)-3,6-dihydro-2H-imidazo[2,1-b][1,3]thiazol-4-ium-5-ol;bromide::7-(2-methylphenyl)-5-(4-methylphenyl)-3,6-dihydro-2H-imidazo[2,1-b]thiazol-4-ium-5-ol;bromide::7-(o-tolyl)-5-(p-tolyl)-3,6-dihydro-2H-imidazo[2,1-b]thiazol-4-ium-5-ol;bromide::MLS000723082::SMR000236036::cid_12005930

SMILES Cc1ccc2[nH]c3c(=O)n(CCC(=O)N4CCN(c5cccc(Cl)c5Cl)CC4)cnc3c2c1

InChI Key InChIKey=RNJKCXKJZCORTR-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 83321   

TargetThiamine pyrophosphokinase 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 83321BDBM83321(3-(3-(4-(2,3-dichlorophenyl)piperazin-1-yl)-3-oxop...)
Affinity DataEC50:  110nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent