BDBM83341 1-(5-fluoro-2-pyrazol-1-yl-benzyl)-4-(tetrahydropyran-2-ylmethyl)isonipecotic acid ethyl ester::1-[[5-fluoro-2-(1-pyrazolyl)phenyl]methyl]-4-(2-oxanylmethyl)-4-piperidinecarboxylic acid ethyl ester::MLS000734872::SMR000317840::cid_16189200::ethyl 1-[(5-fluoranyl-2-pyrazol-1-yl-phenyl)methyl]-4-(oxan-2-ylmethyl)piperidine-4-carboxylate::ethyl 1-[(5-fluoro-2-pyrazol-1-ylphenyl)methyl]-4-(oxan-2-ylmethyl)piperidine-4-carboxylate::ethyl 1-[5-fluoro-2-(1H-pyrazol-1-yl)benzyl]-4-(tetrahydro-2H-pyran-2-ylmethyl)piperidine-4-carboxylate

SMILES Cc1cc2c(C(N)=O)c(N)n(-c3c(C)cc(F)c(O)c3C)c2nc1C

InChI Key InChIKey=LCEZHSAFZVIPCZ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 83341   

TargetMembrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 83341BDBM83341(US20250388583, Compound 602)
Affinity DataIC50: 50nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent

TargetTyrosine-protein kinase Lck(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 83341BDBM83341(US20250388583, Compound 602)
Affinity DataIC50: 550nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent