BDBM83354 MLS000733666::SMR000317630::[1-[2-(2-furyl)benzyl]-3-(3-methoxybenzyl)piperidin-3-yl]methanol::[1-[2-(2-furyl)benzyl]-3-m-anisyl-3-piperidyl]methanol::[1-[[2-(2-furanyl)phenyl]methyl]-3-[(3-methoxyphenyl)methyl]-3-piperidinyl]methanol::[1-[[2-(furan-2-yl)phenyl]methyl]-3-[(3-methoxyphenyl)methyl]piperidin-3-yl]methanol::cid_16191320

SMILES Cc1cc2c(C(N)=O)c(N)n(-c3c(C)c(O)cc(Cl)c3C)c2nc1C

InChI Key InChIKey=BIYPQECYHGGIJC-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 83354   

TargetMembrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 83354BDBM83354(US20250388583, Compound 619 | US20260001879, Compo...)
Affinity DataIC50: 50nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent

TargetMyelin transcription factor 1(Human)
Broad Institute

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 83354BDBM83354(US20250388583, Compound 619 | US20260001879, Compo...)
Affinity DataIC50: 200nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2026
Entry Details
US Patent

TargetMyelin transcription factor 1(Human)
Broad Institute

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 83354BDBM83354(US20250388583, Compound 619 | US20260001879, Compo...)
Affinity DataIC50: 200nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2026
Entry Details
US Patent

TargetMyelin transcription factor 1(Human)
Broad Institute

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 83354BDBM83354(US20250388583, Compound 619 | US20260001879, Compo...)
Affinity DataIC50: 200nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2026
Entry Details
US Patent