BDBM83404 2-(4-benzhydrylpiperazin-1-yl)-1-phenylethanol::2-(4-benzhydrylpiperazino)-1-phenyl-ethanol::2-[4-(diphenylmethyl)-1-piperazinyl]-1-phenylethanol::2-[4-(diphenylmethyl)piperazin-1-yl]-1-phenyl-ethanol::MLS001181737::SMR000567424::cid_2809776

SMILES Cc1ccc2[nH]c3c(=O)n(CCC(=O)N4CCN(c5cc(C(F)(F)F)cc(C(F)(F)F)c5)CC4)cnc3c2c1

InChI Key InChIKey=QCVZMJCLXHNXEV-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 83404   

TargetThiamine pyrophosphokinase 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 83404BDBM83404(3-(3-(4-(3,5-bis(trifluoromethyl)phenyl)piperazin-...)
Affinity DataEC50:  360nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent