BDBM83408 4-chloranyl-N-[[1-(dimethylamino)cyclohexyl]methyl]-3-sulfamoyl-benzamide::4-chloro-N-[[1-(dimethylamino)cyclohexyl]methyl]-3-sulfamoyl-benzamide::4-chloro-N-[[1-(dimethylamino)cyclohexyl]methyl]-3-sulfamoylbenzamide::MLS001171261::SMR000588958::cid_2447253

SMILES Cc1ccc(C)c(N2CCN(C(=O)CCn3cnc4c([nH]c5ccc(C)cc54)c3=O)CC2)c1

InChI Key InChIKey=KPZHOYVIVXYJQK-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 83408   

TargetThiamine pyrophosphokinase 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 83408BDBM83408(3-(3-oxo-3-(4-(3-(trifluoromethyl)benzyl)piperazin...)
Affinity DataEC50:  1.37E+3nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent