BDBM83411 2-(4-bromophenyl)-N-[2-(dimethylamino)-2-phenyl-ethyl]acetamide::2-(4-bromophenyl)-N-[2-(dimethylamino)-2-phenyl-ethyl]ethanamide::2-(4-bromophenyl)-N-[2-(dimethylamino)-2-phenylethyl]acetamide::MLS001175335::SMR000596070::cid_4587627

SMILES COc1cccc(N2CCN(C(=O)Cn3cnc4c([nH]c5ccc(C)cc54)c3=O)CC2)c1

InChI Key InChIKey=FHCPLXLTFFPFFI-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 83411   

TargetThiamine pyrophosphokinase 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 83411BDBM83411(3-(6-methyl-4-oxo-4,5-dihydro-3H-pyrimido[5,4-b]in...)
Affinity DataEC50:  1.22E+3nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent