BDBM83415 2-[2-(3-chloro-4-methoxy-anilino)-2-keto-ethoxy]-N-[2-(dimethylamino)-2-phenyl-ethyl]benzamide::2-[2-(3-chloro-4-methoxyanilino)-2-oxoethoxy]-N-[2-(dimethylamino)-2-phenylethyl]benzamide::2-[2-[(3-chloranyl-4-methoxy-phenyl)amino]-2-oxidanylidene-ethoxy]-N-[2-(dimethylamino)-2-phenyl-ethyl]benzamide::MLS001172480::SMR000591678::cid_3319690

SMILES O=C(CCn1cnc2c([nH]c3ccc(C(F)(F)F)cc32)c1=O)N1CCN(Cc2cc(F)c(F)c(F)c2)CC1

InChI Key InChIKey=PWSLNADMFIPTSL-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 83415   

TargetThiamine pyrophosphokinase 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 83415BDBM83415(3-((3-(8-methyl-4-oxo-4,5-dihydro-3H-pyrimido[5,4-...)
Affinity DataEC50:  1.68E+3nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent