BDBM83418 MLS001166782::N-[2-(dimethylamino)-2-[4-(dimethylamino)phenyl]ethyl]-2-(1-naphthalenyl)acetamide::N-[2-(dimethylamino)-2-[4-(dimethylamino)phenyl]ethyl]-2-(1-naphthyl)acetamide::N-[2-(dimethylamino)-2-[4-(dimethylamino)phenyl]ethyl]-2-naphthalen-1-yl-ethanamide::N-[2-(dimethylamino)-2-[4-(dimethylamino)phenyl]ethyl]-2-naphthalen-1-ylacetamide::SMR000641460::cid_18564899

SMILES Cc1ccc2oc3c(=O)n(CCC(=O)N4CCN(c5cccc(C(F)(F)F)c5)CC4)cnc3c2c1

InChI Key InChIKey=QVKPANHKYGHYNJ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 83418   

TargetThiamine pyrophosphokinase 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 83418BDBM83418(3-(8-methyl-4-oxobenzofuro[3,2-d]pyrimidin-3(4H)-y...)
Affinity DataEC50:  1.19E+3nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent