BDBM83421 MLS000950173::N-[4-[2-(2,4-dimethylphenoxy)ethanoylamino]phenyl]thiophene-2-carboxamide::N-[4-[[2-(2,4-dimethylphenoxy)-1-oxoethyl]amino]phenyl]-2-thiophenecarboxamide::N-[4-[[2-(2,4-dimethylphenoxy)acetyl]amino]phenyl]thiophene-2-carboxamide::SMR000619982::cid_1016249

SMILES Cc1ccc2[nH]c3c(=O)n(CCC(=O)NCc4cccc(C(F)(F)F)c4)ccc3c2c1

InChI Key InChIKey=JNOUJXYFQNKREP-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 83421   

TargetThiamine pyrophosphokinase 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 83421BDBM83421(N-(2-(methyl(5,6,7,8-tetrahydronaphthalen-1-yl)ami...)
Affinity DataEC50:  1.20E+3nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent