BDBM83437 2-chloranyl-5-(4-ethylpiperazin-1-yl)sulfonyl-N-(2-phenylethyl)-N-(phenylmethyl)benzamide::2-chloro-5-[(4-ethyl-1-piperazinyl)sulfonyl]-N-(2-phenylethyl)-N-(phenylmethyl)benzamide::MLS002179937::N-benzyl-2-chloro-5-(4-ethylpiperazin-1-yl)sulfonyl-N-(2-phenylethyl)benzamide::N-benzyl-2-chloro-5-(4-ethylpiperazino)sulfonyl-N-phenethyl-benzamide::SMR001268967::cid_25162458

SMILES O=C(CCn1cnc2c(oc3ccc(F)cc32)c1=O)N1CCN(c2cccc(C(F)(F)F)c2)CC1

InChI Key InChIKey=UJMSRLDUMIFPLQ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 83437   

TargetThiamine pyrophosphokinase 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 83437BDBM83437(US20250388584, Example 148)
Affinity DataEC50:  1.99E+3nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent