BDBM8344 6-aryl-pyrazolo[3,4-b]pyridine analogue 8::CHEMBL408019::N-[6-(3-hydroxyphenyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]cyclopropanecarboxamide::pyrazolo[3,4-b]pyridine analogue 10
SMILES Oc1cccc(c1)-c1ccc2c(NC(=O)C3CC3)n[nH]c2n1
InChI Key InChIKey=AXWDQRXGOKDXJT-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 8344
Affinity DataIC50: 12nMpH: 7.0 T: 22°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 10 uM ATP/ [gamma-33P] ATP. Aft...More data for this Ligand-Target Pair
Affinity DataIC50: 62nMAssay Description:In vitro kinase assay using purified CDK2/Cyclin A was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP...More data for this Ligand-Target Pair
Affinity DataKd: 150nMAssay Description:Binding affinity to human SKMLCKMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant GSK3-betaMore data for this Ligand-Target Pair
Affinity DataKd: 207nMAssay Description:Binding affinity to human MARK1More data for this Ligand-Target Pair
Affinity DataKd: 16nMAssay Description:Binding affinity to human PIM2More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
Affinity DataKd: >4.00E+4nMAssay Description:Binding affinity to human MPSK1More data for this Ligand-Target Pair