BDBM83458 1-[2-[2-(1-oxo-2-triphenylphosphoranylideneethyl)phenyl]phenyl]-2-triphenylphosphoranylideneethanone::2-(triphenyl--phosphanylidene)-1-[2-[2-[2-(triphenyl--phosphanylidene)acetyl]phenyl]phenyl]ethanone::2-(triphenyl--phosphanylidene)-1-[2-[2-[2-(triphenyl--phosphanylidene)ethanoyl]phenyl]phenyl]ethanone::2-triphenylphosphoranylidene-1-[2-[2-(2-triphenylphosphoranylideneacetyl)phenyl]phenyl]ethanone::MLS002702210::SMR001565773::cid_381571

SMILES CC1(NS(=O)(=O)c2ccc3c4c(N5CCN(C(=O)C6CC6)CC5)ncnc4n(-c4nnc(C(F)F)s4)c3c2)CC1

InChI Key InChIKey=HMLIJGSRQAHTFN-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 83458   

TargetPoly(ADP-ribose) glycohydrolase(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 83458BDBM83458(US20250388589, Example 1)
Affinity DataIC50: 0.000100nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent