BDBM83460 2,6-bis(diethylaminomethyl)-4-[(10-methyl-11-indolo[3,2-b]quinolinyl)amino]phenol;hydrochloride::2,6-bis(diethylaminomethyl)-4-[(10-methylindolo[3,2-b]quinolin-11-yl)amino]phenol;hydrochloride::2,6-bis(diethylaminomethyl)-4-[(10-methylquindolin-11-yl)amino]phenol;hydrochloride::MLS002701585::SMR001565186::cid_376179

SMILES O=C(CCN1c2ccccc2Sc2ccccc21)NCCN1CCOCC1

InChI Key InChIKey=YQEMYONMNJQBMH-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 83460   

TargetThiamine pyrophosphokinase 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 83460BDBM83460(US20250388584, Example 200)
Affinity DataEC50:  2.94nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent