BDBM83792 (2-aminophenyl)-[3-(trifluoromethyl)phenyl]amine::2-N-[3-(trifluoromethyl)phenyl]benzene-1,2-diamine::MLS000755670::N2-[3-(trifluoromethyl)phenyl]benzene-1,2-diamine::N~1~-[3-(trifluoromethyl)phenyl]-1,2-benzenediamine::SMR000337335::cid_3729763

SMILES C[C@H]1CN(c2ncnc3c2c2ccc(S(=O)(=O)NC4(C#N)CC4)cc2n3-c2nnc(C(F)F)s2)CCO1

InChI Key InChIKey=AWUGJXBGADQEFJ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 83792   

TargetPoly(ADP-ribose) glycohydrolase(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 83792BDBM83792((S)-N-(1-Cyanocyclopropyl)-9-(5- (difluoromethyl)-...)
Affinity DataIC50: 0.000100nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent