BDBM85286 2-(benzo[d]isothiazol-3-ylimino)-5-benzylidenethiazolidin-4-one, 5b

SMILES Clc1ccc(\C=C2\S\C(NC2=O)=N/c2nsc3ccccc23)cc1

InChI Key InChIKey=PUFLXTPEEIWEIM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 85286   

TargetCollagenase 3(Human)
University of Catania

LigandPNGBDBM85286(2-(benzo[d]isothiazol-3-ylimino)-5-benzylidenethia...)
Affinity DataIC50: 2.50E+4nMpH: 7.0 T: 2°CAssay Description:The MMP assay were performed evaluating the ability of compounds 1a-6a and 1b-6b to prevent the hydrolysis of the fluorescence-quenched peptide subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
University of Catania

LigandPNGBDBM85286(2-(benzo[d]isothiazol-3-ylimino)-5-benzylidenethia...)
Affinity DataIC50: 6.50E+4nMpH: 7.0 T: 2°CAssay Description:The MMP assay were performed evaluating the ability of compounds 1a-6a and 1b-6b to prevent the hydrolysis of the fluorescence-quenched peptide subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2012
Entry Details Article
PubMed