BDBM8538 4-[(1E)-{2-[7-(3-methoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]hydrazin-1-ylidene}methyl]pyridine::heterocyclic pyrimidyl hydrazone 4

SMILES COc1cccc(c1)-n1ccc2c(N=NCc3ccncc3)ncnc12

InChI Key InChIKey=USZWAQBLCQQUNG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 8538   

TargetGlycogen synthase kinase-3 beta(Human)
Glaxosmithkline

LigandPNGBDBM8538(4-[(1E)-{2-[7-(3-methoxyphenyl)-7H-pyrrolo[2,3-d]p...)
Affinity DataIC50: 31.6nMpH: 7.2 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-33P] ATP. Af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2006
Entry Details Article
PubMed