BDBM8559 4-Acylamino-6-arylfuro[2,3-d]pyrimidine 4::N-[6-(4-methoxyphenyl)furo[2,3-d]pyrimidin-4-yl]hexanamide

SMILES CCCCCC(=O)Nc1ncnc2oc(cc12)-c1ccc(OC)cc1

InChI Key InChIKey=ZYZXVKYLMUKBGC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 8559   

TargetGlycogen synthase kinase-3 beta(Human)
Tsukuba Research Laboratories

LigandPNGBDBM8559(N-[6-(4-methoxyphenyl)furo[2,3-d]pyrimidin-4-yl]he...)
Affinity DataIC50: 437nMpH: 7.2 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-32P] ATP. Af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Tsukuba Research Laboratories

LigandPNGBDBM8559(N-[6-(4-methoxyphenyl)furo[2,3-d]pyrimidin-4-yl]he...)
Affinity DataIC50: 1.90E+4nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-32P] ATP. Af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2006
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Tsukuba Research Laboratories

LigandPNGBDBM8559(N-[6-(4-methoxyphenyl)furo[2,3-d]pyrimidin-4-yl]he...)
Affinity DataIC50: 4.80E+4nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-32P] ATP. Af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2006
Entry Details Article
PubMed