BDBM85602 (R)-BUTAPROST::Butaprost (Free Acid)::CAS_69648-38-0

SMILES CCCC1(CCC1)[C@H](O)C\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(=O)OC

InChI Key InChIKey=XRISENIKJUKIHD-UHFFFAOYSA-N

Data  12 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 85602   

TargetProstaglandin E2 receptor EP2 subtype(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 85602BDBM85602((R)-BUTAPROST | CAS_69648-38-0 | Butaprost (Free A...)
Affinity DataEC50:  33nMAssay Description:Agonist activity at EP2 receptor (unknown origin) by functional assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetProstacyclin receptor(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 85602BDBM85602((R)-BUTAPROST | CAS_69648-38-0 | Butaprost (Free A...)
Affinity DataIC50: 37nMAssay Description:Agonist activity at prostanoid IP receptor (unknown origin) by functional assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 85602BDBM85602((R)-BUTAPROST | CAS_69648-38-0 | Butaprost (Free A...)
Affinity DataKi:  91nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Merck Frosst Centre For Therapeutic Research

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 85602BDBM85602((R)-BUTAPROST | CAS_69648-38-0 | Butaprost (Free A...)
Affinity DataKi:  1.64E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 85602BDBM85602((R)-BUTAPROST | CAS_69648-38-0 | Butaprost (Free A...)
Affinity DataKi:  2.40E+3nMAssay Description:Binding affinity to EP2 receptor (unknown origin) by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 85602BDBM85602((R)-BUTAPROST | CAS_69648-38-0 | Butaprost (Free A...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to EP1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetProstacyclin receptor(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 85602BDBM85602((R)-BUTAPROST | CAS_69648-38-0 | Butaprost (Free A...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMed
TargetProstaglandin F2-alpha receptor(Human)
Merck Frosst Centre For Therapeutic Research

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 85602BDBM85602((R)-BUTAPROST | CAS_69648-38-0 | Butaprost (Free A...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 85602BDBM85602((R)-BUTAPROST | CAS_69648-38-0 | Butaprost (Free A...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to EP4 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 85602BDBM85602((R)-BUTAPROST | CAS_69648-38-0 | Butaprost (Free A...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMed
TargetSolute carrier organic anion transporter family member 2A1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 85602BDBM85602((R)-BUTAPROST | CAS_69648-38-0 | Butaprost (Free A...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMed
TargetHematopoietic prostaglandin D synthase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 85602BDBM85602((R)-BUTAPROST | CAS_69648-38-0 | Butaprost (Free A...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMed
TargetProstacyclin receptor(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 85602BDBM85602((R)-BUTAPROST | CAS_69648-38-0 | Butaprost (Free A...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to prostanoid IP receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Merck Frosst Centre For Therapeutic Research

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 85602BDBM85602((R)-BUTAPROST | CAS_69648-38-0 | Butaprost (Free A...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to EP3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed