BDBM86099 2-Cyanopyrrolidine Derivative, 28

SMILES O=C(NC(Cc1ccccc1)C(=O)N1CCC[C@H]1C#N)C(=C\c1ccccc1)\c1ccccc1

InChI Key InChIKey=PSZLCIZOFNZDLI-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 86099   

TargetCathepsin B(Human)
The M. S. University of Baroda

LigandPNGBDBM86099(2-Cyanopyrrolidine Derivative, 28)
Affinity DataKi:  7.50E+4nM ΔG°:  -5.59kcal/molepH: 6.0 T: 2°CAssay Description:The fluorescence for the assay was monitored on a Varian Gemini spectrofluorometer with the excitation and emission wavelengths at 380 and 440nm. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2012
Entry Details Article
PubMed
TargetCathepsin B(Human)
The M. S. University of Baroda

LigandPNGBDBM86099(2-Cyanopyrrolidine Derivative, 28)
Affinity DataKi: >1.00E+5nM ΔG°: >-5.42kcal/molepH: 6.0 T: 2°CAssay Description:The fluorescence for the assay was monitored on a Varian Gemini spectrofluorometer with the excitation and emission wavelengths at 380 and 440nm. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2012
Entry Details Article
PubMed