BDBM86845 1-(2,6-difluorophenyl)-3-(4-(4-(2-isopropoxyphenyl)piperazin-1-yl)cyclohexyl)urea::CAS_16041630::NSC_16041630

SMILES CC(C)Oc1ccccc1N1CCN(CC1)C1CCC(CC1)NC(=O)Nc1c(F)cccc1F

InChI Key InChIKey=GRLCSEWTOACLTP-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 86845   

TargetD(2) dopamine receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by PDSP Ki Database
LigandPNGBDBM86845(NSC_16041630 | CAS_16041630 | 1-(2,6-difluoropheny...)
Affinity DataKi:  2.40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2012
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by PDSP Ki Database
LigandPNGBDBM86845(NSC_16041630 | CAS_16041630 | 1-(2,6-difluoropheny...)
Affinity DataKi:  4.80nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2012
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by PDSP Ki Database
LigandPNGBDBM86845(NSC_16041630 | CAS_16041630 | 1-(2,6-difluoropheny...)
Affinity DataKi:  5.30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by PDSP Ki Database
LigandPNGBDBM86845(NSC_16041630 | CAS_16041630 | 1-(2,6-difluoropheny...)
Affinity DataKi:  22nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2012
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by PDSP Ki Database
LigandPNGBDBM86845(NSC_16041630 | CAS_16041630 | 1-(2,6-difluoropheny...)
Affinity DataKi:  36nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2012
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by PDSP Ki Database
LigandPNGBDBM86845(NSC_16041630 | CAS_16041630 | 1-(2,6-difluoropheny...)
Affinity DataKi:  52nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2012
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by PDSP Ki Database
LigandPNGBDBM86845(NSC_16041630 | CAS_16041630 | 1-(2,6-difluoropheny...)
Affinity DataKi:  92nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2012
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by PDSP Ki Database
LigandPNGBDBM86845(NSC_16041630 | CAS_16041630 | 1-(2,6-difluoropheny...)
Affinity DataKi:  299nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2012
Entry Details Article
PubMed