BDBM8732 (2E)-N-methyl-N-[(1-methyl-1H-indol-2-yl)methyl]-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)prop-2-enamide::(E)-N-Methyl-N-(1-methyl-1H-indol-2-ylmethyl)-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)acrylamide::indole naphthyridinone 21
SMILES CN(Cc1cc2ccccc2n1C)C(=O)\C=C\c1cnc2NC(=O)CCc2c1
InChI Key InChIKey=TVPFKRZTBLHFFW-JXMROGBWSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 8732
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus (strain MRSA252))
Glaxosmithkline
Glaxosmithkline
Affinity DataIC50: 50nMpH: 6.5 T: 30°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] FabI(Haemophilus influenzae (strain ATCC 51907 / DSM 11...)
Glaxosmithkline
Glaxosmithkline
Affinity DataIC50: 560nMT: 30°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] FabI(Escherichia coli (strain K12))
Affinium Pharmaceuticals
Curated by ChEMBL
Affinium Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 139nMAssay Description:Inhibition of Escherichia coli FabI assessed as effect on NAD(P)H consumptionMore data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus (strain MRSA252))
Glaxosmithkline
Glaxosmithkline
Affinity DataIC50: 50nMAssay Description:Inhibition of Staphylococcus aureus FabIMore data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] FabI(Escherichia coli (strain K12))
Affinium Pharmaceuticals
Curated by ChEMBL
Affinium Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of Escherichia coli FabIMore data for this Ligand-Target Pair