BDBM88452 US20250388593, Example 56::tert-Butyl 6-(1,3-dioxo-2,11-diazaspiro [6.7]tetradecan-11-yl) pyridine-3-carboxylate

SMILES CC(C)(C)OC(=O)c1ccc(N2CCCC3(CCCC(=O)NC3=O)CCC2)nc1

InChI Key InChIKey=ORFOUNMQGLWBNX-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 88452   

TargetProtein cereblon [318-426](Human)
Mitsubishi Tanabe Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 88452BDBM88452(tert-Butyl 6-(1,3-dioxo-2,11-diazaspiro [6.7]tetra...)
Affinity DataKd:  7.50E+4nMAssay Description:Data Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent