BDBM8851 3-(4-{4-amino-6-[(4-methylpiperazin-1-yl)methyl]thieno[2,3-d]pyrimidin-5-yl}phenyl)-1-(3-methylphenyl)urea::N-(4-{4-Amino-6-[(4-methylpiperazin-1-yl)methyl]-thieno[2,3-d]pyrimidin-5-yl}phenyl)-N¢-(3-methylphenyl)urea::Thienopyrimidine deriv. 60

SMILES CN1CCN(Cc2sc3ncnc(N)c3c2-c2ccc(NC(=O)Nc3cccc(C)c3)cc2)CC1

InChI Key InChIKey=PHWICBBDBJYOQR-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 8851   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM8851(3-(4-{4-amino-6-[(4-methylpiperazin-1-yl)methyl]th...)
Affinity DataIC50:  590nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM8851(3-(4-{4-amino-6-[(4-methylpiperazin-1-yl)methyl]th...)
Affinity DataIC50:  800nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM8851(3-(4-{4-amino-6-[(4-methylpiperazin-1-yl)methyl]th...)
Affinity DataIC50:  630nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM8851(3-(4-{4-amino-6-[(4-methylpiperazin-1-yl)methyl]th...)
Affinity DataIC50:  631nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM8851(3-(4-{4-amino-6-[(4-methylpiperazin-1-yl)methyl]th...)
Affinity DataIC50:  589nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM8851(3-(4-{4-amino-6-[(4-methylpiperazin-1-yl)methyl]th...)
Affinity DataIC50:  794nMAssay Description:Inhibition of cKITMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM8851(3-(4-{4-amino-6-[(4-methylpiperazin-1-yl)methyl]th...)
Affinity DataIC50:  800nMAssay Description:Inhibition of c-Kit by HTRF methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed