BDBM88519 US20250388593, Example 115::tert-Butyl 2-(2,4-dioxo-1,3-diazepan-1-yl) thiazole-5-carboxylate

SMILES CC(C)(C)OC(=O)c1cnc(N2CCCC(=O)NC2=O)s1

InChI Key InChIKey=OSGXCWPHMSTUKD-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 88519   

TargetProtein cereblon [318-426](Human)
Mitsubishi Tanabe Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 88519BDBM88519(tert-Butyl 2-(2,4-dioxo-1,3-diazepan-1-yl) thiazol...)
Affinity DataKd:  7.50E+4nMAssay Description:Data Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent