BDBM88578 US20250388593, Example 136::tert-Butyl (E)-3-[1-(2,7-oxazepan-3-yl)indazol-3-yl]-2-propenoate

SMILES CC(C)(C)OC(=O)/C=C/c1nn(C2CCCC(=O)NC2=O)c2ccccc12

InChI Key InChIKey=VDZUYXGWEODYRC-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 88578   

TargetProtein cereblon [318-426](Human)
Mitsubishi Tanabe Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 88578BDBM88578(tert-Butyl (E)-3-[1-(2,7-oxazepan-3-yl)indazol-3-y...)
Affinity DataKd:  7.50E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent