BDBM92814 Bisanilinopyrimidine, 6g::US9249124, 30

SMILES N#Cc1ccccc1Nc1ccnc(Nc2ccccc2)n1

InChI Key InChIKey=HGDMSLNGNHAVPL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 92814   

TargetAurora kinase A(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 92814BDBM92814(Bisanilinopyrimidine, 6g | US9249124, 30)
Affinity DataIC50: 560nMpH: 7.4 T: 2°CAssay Description:Reactions were carried out at room temperature in 15 mM HEPES buffer (pH 7.4) containing 20 mM NaCl, 1 mM EGTA, 0.02% Tween 20, 10 mM MgCl2, 5% (v/v)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2017
Entry Details
US Patent

TargetAurora kinase A(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 92814BDBM92814(Bisanilinopyrimidine, 6g | US9249124, 30)
Affinity DataIC50: 560nMAssay Description:In vitro enzyme activity assay using Aurora Kinase A. More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2013
Entry Details Article
PubMed