BDBM93340 EN300-270265::Integrase inhibitor, R1{4}

SMILES NCc1cc(Cl)cc(Cl)c1

InChI Key InChIKey=ICIJWOWQUHHETJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 93340   

TargetReplicase polyprotein 1ab(2019-nCoV)
Cornell University

LigandPNGBDBM93340(Integrase inhibitor, R1{4} | EN300-270265)
Affinity DataIC50: 78nMAssay Description:IC50 values were determined using 12 point 2-fold dilutions (starting from 10 μM).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Cornell University

LigandPNGBDBM93340(Integrase inhibitor, R1{4} | EN300-270265)
Affinity DataIC50: 110nMAssay Description:IC50 values were determined using 12 point 2-fold dilutions (starting from 10 μM).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Cornell University

LigandPNGBDBM93340(Integrase inhibitor, R1{4} | EN300-270265)
Affinity DataIC50: 1.72E+3nMAssay Description:IC50 values were determined for the whole plate in case of Chan-Lam coupling, using 5 point 3-fold dilutions (starting from 10 μM).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2023
Entry Details
PubMed
TargetGag-Pol polyprotein(HIV-1)
Bristol-Myers Squibb

LigandPNGBDBM93340(Integrase inhibitor, R1{4} | EN300-270265)
Affinity DataIC50: 2.47E+3nMAssay Description:Inhibition assay using HIV-1 integrase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2013
Entry Details Article
PubMed