BDBM9450 7-Methoxy-3-phenyl-2-[(3-pyridylmethyl)thio]-4H-1-benzopyran-4-one::7-methoxy-3-phenyl-2-[(pyridin-3-ylmethyl)sulfanyl]-4H-chromen-4-one::CHEMBL185819::Isoflavone 3f

SMILES COc1ccc2c(c1)oc(SCc1cccnc1)c(-c1ccccc1)c2=O

InChI Key InChIKey=IDRBMTDNAZIORH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 9450   

TargetAromatase(Human)
Ohio State University

LigandPNGBDBM9450(7-methoxy-3-phenyl-2-[(pyridin-3-ylmethyl)sulfanyl...)
Affinity DataIC50: 9.20E+3nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Ohio State University

LigandPNGBDBM9450(7-methoxy-3-phenyl-2-[(pyridin-3-ylmethyl)sulfanyl...)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of human aromatase-mediated conversion of [1beta3H]androstenedione to estrone by liquid scintillation counting in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed