BDBM9454 7-(benzyloxy)-3-phenyl-2-[(pyridin-4-ylmethyl)sulfanyl]-4H-chromen-4-one::CHEMBL188664::Isoflavone 3j
SMILES O=c1c(-c2ccccc2)c(SCc2ccncc2)oc2cc(OCc3ccccc3)ccc12
InChI Key InChIKey=LETKTNKPQWCFSX-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 9454
Affinity DataKi: 220nMAssay Description:Inhibition of human placental microsome aromatase using [1beta[3H]]androst-4-ene-3,17-dione as substrate after 15 mins in presence of NADPH by liquid...More data for this Ligand-Target Pair
Affinity DataKi: 220nM ΔG°: -9.44kcal/mole IC50: 210nMpH: 7.0 T: 37°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Inhibition of human placental microsome aromatase using [1beta[3H]]androst-4-ene-3,17-dione as substrate after 15 mins in presence of NADPH by liquid...More data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+5nMAssay Description:Inhibition of human placental aromatase assessed as conversion of [1beta-3H]androst-4-ene-3,17-dione to estrone after 15 mins by scintillation counti...More data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Inhibition of human aromatase-mediated conversion of [1beta3H]androstenedione to estrone by liquid scintillation counting in presence of NADPHMore data for this Ligand-Target Pair