BDBM9455 3-(4-Methoxyphenyl)-7-(phenylmethoxy)-2-[(4-pyridylmethyl)thio]4H-1-benzopyran-4-one::7-(benzyloxy)-3-(4-methoxyphenyl)-2-[(pyridin-4-ylmethyl)sulfanyl]-4H-chromen-4-one::CHEMBL186079::Isoflavone 3k

SMILES COc1ccc(cc1)-c1c(SCc2ccncc2)oc2cc(OCc3ccccc3)ccc2c1=O

InChI Key InChIKey=RLOJJLAHGWEVQX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 9455   

TargetAromatase(Human)
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM9455(CHEMBL186079 | 3-(4-Methoxyphenyl)-7-(phenylmethox...)
Affinity DataIC50: 530nMAssay Description:Inhibition of human aromatase-mediated conversion of [1beta3H]androstenedione to estrone by liquid scintillation counting in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAromatase(Human)
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM9455(CHEMBL186079 | 3-(4-Methoxyphenyl)-7-(phenylmethox...)
Affinity DataIC50: 530nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2006
Entry Details Article
PubMed